THE EXTRACYTOPLASMIC DOMAIN OF THE MYCOBACTERIUM TUBERCULOSIS SER/THR KINASE PKNB BINDS SPECIFIC MUROPEPTIDES AND IS REQUIRED FOR PKNB LOCALIZATION.

The extracytoplasmic domain of the Mycobacterium tuberculosis Ser/Thr kinase PknB binds specific muropeptides and is required for PknB localization.

The Mycobacterium tuberculosis Ser/Thr kinase PknB has been implicated in the regulation of cell growth and morphology in this organism.The extracytoplasmic domain of this membrane protein comprises four penicillin binding protein and Ser/Thr CAYENNE EXTRA HOT kinase associated (PASTA) domains, which are predicted to bind stem peptides of peptidogl

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Repeated Demographic-Structural Crises Propel the Spread of Large-scale Agrarian States Throughout the Old World

I investigate EYE SHADOW DUSKY WOODS #1520 the geographical consequences of demographic-structural dynamics using a spatially resolved agent-based model of agrarian empires in several Old World regions between 1500 BCE and 1500 CE.I estimate and bound key model parameters from two historical datasets.Although several very large-scale polities (e.g.

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